Discovered in the late 1940s, Tetracyclines are a family of broad spectrum antibiotics used to treat a wide range of bacterial infections. The original tetracyclines were derived from Streptomyces bacteria, but the newer derivatives are semisynthetic.

The tetracycline antibiotics are the workhorses in oral acne therapy. They're the first-line oral antibiotic drugs of choice in the management of moderate to severe acne. They were first widely prescribed by dermatologists in the early 1950s when...
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